Recommendations for the use of T3
Levothyroxine sodium (T-4), liothyronine sodium (T-3) – is farmed natural form of thyroid hormone.
Thyroid hormones are primarily responsible for regulating the rate of metabolism in the body and play an important role in the disposal of body proteins, fats and carbohydrates.
Levothyroxine sodium is used in medicine for the treatment of cases of hypothyroidism, which is characterized by insufficient production of natural thyroid hormone. This can occur with a number of symptoms including loss of energy, lethargy, weight gain, hair loss, and changes in skin texture. Levothyroxine sodium is considered delayed action cure, can be used and 4 to 6 weeks to complete balanced sufficient therapeutic levels. It is also the most commonly prescribed for the treatment of the thyroid gland in the world and is widely regarded as the standard form of treatment for most cases of hypothyroidism. Action levothyroxine sodium is very similar to the action of the popular drug Lionine T3 (Sodium Liothyronine).
Lionine -T3 is slightly different in its structure, however, being a synthetic form of thyroid hormone triiodothyronine (T 3) it provides cover those effects only in a stronger form.
Healthy people have a sufficient level of both T-3 and T 4 thyroid hormones are present in their bodies. T-3 is considered the main active form of thyroid hormone, while the T-4 is used primarily as a reserve for the T-3, providing most of their metabolic activity by conversion in the peripheral tissues. T-3 is regarded as a group of moschny schetovidnoy gland hormones, and its action is about four times stronger than that of T-4. In addition, Lionine -T3 considered more effective form of thyroid medication, both in terms of activity and in reducing adverse events.
Levothyroxine sodium is appreciated by many who use steroids by athletes and bodybuilders for its ability to stimulate the metabolic rate and support the disintegration of fat reserves. The drug is usually taken during caloric restriction (predsorevnovatelny period, or out of the loop) when an individual is oriented to increase loss of fat or muscle seal. At the use of thyroid hormones in the body at a higher level is maintained fat loss, thus that can not limit itself to the calorie intake of food.
Anabolic steroids are usually used in conjunction with these hormones, and many believe that the increased metabolic effect of these drugs may lead to more rapid progress to muscle adjustment. However, the widespread use of drugs, for this purpose, so until the end of neisledovanno, and the question to accept or not, in order to achieve these goals, a purely personal matter, although athletes are all as one claim that drugs give a positive result, the main thing is not to experiment with the dosage, exceeding it to the extreme limits.
Structural Features
Levothyroxine sodium is a synthetic form of the thyroid hormone T4 has the chemical name L- 3,3 ‘, 5,5’ – tetraiodothyronine sodium salt.
Dosage and recommendations
When used for treatment of mild to moderate forms of hypothyroidism, the mean dose of levothyroxine sodium is approximately 100-125 g per day. The full therapeutic dose can be adopted without a pyramidal receiving, in healthy adult patients. It should be noted that because of the long half-life of levothyroxine peak therapeutic effect for a given dose, may be achieved by 4 to 6 weeks.
When used (off-label) to fast fat loss bodybuilders and athletes, a typical protocol includes a slow build-up dose, so that the body and the body had enough time to adjust to izmenyayuschimusya level of thyroid hormone. Athletes tend to start with a low dose of 25-50 mg, and gradually increase the amount of 25-50 mg every day or every other day. The ultimate dosage will typically be in the range 100-150 mg per day, and rarely more than 250 micrograms. It is important to remember that thyroid drugs are potent drugs with significant potential side effects. So you should be careful when it is used, should also be aware that an excessive amount of levothyroxine sodium should not last more than eight weeks of cycle. You also need to comply with the rule, at the beginning of the cycle to increase the dosage, as out of the loop, the dosage is gradually umenshat.Eto usually achieved by reducing the dose by 25 mg every second or third day. The emphasis here, again, is placed on the to avoid any sudden changes in hormone levels that could cause side effects. Please note that due to the slow action of levothyroxine sodium, the active drug is completely excreted from the body, it may take several weeks.
Side effects
The side effects usually associated with overdose, and may include headache, irritability, nervousness, sweating, irregular heartbeat, increased bowel motility, or menstrual irregularities. Overdose can also cause shock and can exacerbate or provoke angina or stagnant heart failure. When stkrytyh chronic ailments, excessive intake of levothyroxine sodium will produce the symptoms commonly associated with hyperthyroidism or the overproduction of natural thyroid hormone. The occurrence of side effects manifest themselves, usually causes an immediate decrease the dosage or completely discontinue therapy of levothyroxine sodium. Acute massive overdose can be life-threatening.
Tags: Levothyroxine sodium, T-4, T3